The show follows the titular 21-year-old Lucy, who lives in San Francisco and has been ordained by her father, the devil, to fulfill her destiny as the Antichrist, whether she likes it or not. Along the way she meets up with a DJ — Jesús — who turns out to be the Second Coming of the messiah and the two begin dating from the first episode after Lucy saves him from a fire created by her father to kill him.
Meanwhile, her father tries different schemes in his quest to take over the world with the help of his "advocate," Becky, who acts as something of a personal assistant. At the same time a group of "Special Clergy," two priests and a nun, are on a mission from the Vaticanto find and destroy Lucy.
He's Not the Messiah, He's the DJ (Episode 1) Edit
Lucy's pet demon dog hypnotizes her new boyfriend into killing himself when she's distracted by a call from her father.